MOTS-C

MOTS-C 10 mg is a mitochondrial-derived peptide research product offered by SARMs Revolution Lab in Canada. MOTS-C is a 16-amino-acid peptide encoded by a short open reading frame within mitochondrial 12S rRNA.

MOTS-C 10 mg research product information

Batch identity and analytical documentation should be reviewed independently. This listing does not claim that the vial reproduces a physiological concentration or a clinical intervention.

What is MOTS-C?

MOTS-C is part of a developing field of mitochondrial-derived peptides: short signalling sequences encoded within mitochondrial DNA. Experimental literature studies its relationship with cellular stress responses, AMPK signalling, folate and purine metabolism, and communication between mitochondria and the nucleus.

The original 2015 publication reported metabolic findings in cells and mice. Later research has explored associations with exercise, ageing and human physiology, but direct therapeutic evidence remains limited. Preclinical findings must not be presented as proof of weight loss, longevity or performance in people.

How is MOTS-C studied?

Research models examine metabolic homeostasis, insulin signalling, skeletal-muscle response, mitochondrial stress and nuclear gene expression. A 2022 study found changes in endogenous MOTS-C expression after physical activity in animal models; this does not establish that administering an external commercial vial produces the same effect in humans.

Study species, assay method, peptide sequence, concentration and outcome should be identified before comparing results. This page does not provide dosage, reconstitution, injection or performance instructions.

MOTS-C evidence limits in Canada

MOTS-C is experimental and should not be represented as an established anti-aging, obesity, diabetes or exercise treatment. Product marketing, research evidence and regulatory authorization are separate questions. Researchers should verify applicable Canadian rules and documentation.

MOTS-C 10 mg frequently asked questions

What does MOTS-C mean?

The name refers to the mitochondrial open reading frame of the 12S rRNA type-c.

How much MOTS-C is supplied?

The SRL listing identifies one 10 mg vial. Confirm the label and batch documentation received.

Is MOTS-C a naturally encoded peptide?

The sequence was identified from a short open reading frame in mitochondrial DNA. A commercial research material still requires its own identity and purity documentation.

Is MOTS-C proven for weight loss or athletic performance?

No. Much of the evidence is preclinical, and controlled human efficacy evidence is not established for this product.

Does this page include a MOTS-C protocol?

No. It does not provide dosing, mixing, injection or self-administration instructions.

Where can related cellular-energy research be reviewed?

See the NAD+ research page and the SRL peptide research category. These links do not recommend combining products.

Scientific references

• Lee C et al. Discovery and metabolic research on MOTS-C. Cell Metabolism. 2015.
• MOTS-C expression following physical activity and experimental exercise research. 2022.
• Review of MOTS-C in muscle and fat metabolism. 2016.

Research-use notice: MOTS-C 10 mg is offered strictly for laboratory research and analytical work. It is not intended for human consumption, self-administration, diagnosis, treatment or veterinary use.